Patients diagnosed early with small tumors can still have aggressive breast cancer. This study was presented at the European Society for Medical Oncology (ESMO) 2017 Congress in Madrid. Researchers found one out of four newly diagnosed breast cancers were aggressive and could benefit from chemotherapy. The study went on to say the aggressive tumors could be identified by a 70 gene signature.
There is a general assumption that smaller tumors are less aggressive, according to the lead author of the study, Dr. Konstantinos Tryfonidis. The MINDACT results, sponsored by the European Organisation for Research and Treatment of Cancer (EORTC), challenge that assumption with statistical research. Researchers analyzed 826 patients, with a primary tumor size less than 1 cm. They found that 196 of those patients were at low clinical risk but high genomic risk.
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